Tissue Engineering Approaches to Cell-Based Type 1 Diabetes Therapy

Cell Replacement Therapy in Type 1 Diabetes

Biomaterial Approaches for Stem Cell-Based Myocardial Tissue Engineering

Adult and pluripotent stem cells represent a ready supply of cellular raw materials that can be used to generate the functionally mature cells needed to replace damaged or diseased heart tissue. However, the use of stem cells for cardiac regenerative therapies is limited by the low efficiency by which stem cells are differentiated in vitro to cardiac lineages as well as the inability to effecti...

Experimental approaches to tissue engineering.

Video Link The video component of this article can be found at http://www.jove.com/video/272/ Disclosures The authors have nothing to disclose.

Autologous Approaches to Tissue Engineering

Stem cells have added a new thrust to tissue engineering. Their distinctive self-renewal and plasticity have not only optimized many tissue engineering developments, but also rendered feasible some applications which would otherwise be unattainable with somatic cells. This review focuses on general aspects of autologous tissue engineering based on so-called adult stem cells, which not only allo...

Cardiac tissue engineering and regeneration using cell-based therapy

Stem cell therapy and tissue engineering represent a forefront of current research in the treatment of heart disease. With these technologies, advancements are being made into therapies for acute ischemic myocardial injury and chronic, otherwise nonreversible, myocardial failure. The current clinical management of cardiac ischemia deals with reestablishing perfusion to the heart but not dealing...